Pioneer Ghana Conference is an administrative unit of the Seventh-day Adventist Church in Ghana. It was formerly part of Mid-South Ghana Conference and was organized in 2017. Pioneer Ghana Conference consists of the following territories: Agona West, and Effutu Municipalities; and the districts of Agona East, Ajumako/Enyam/Essiam, Asikuma/Odoben/Brakwa, Awuru Senya, Awutu Senya East, Gomoa East, and Gomoa West.